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doi: 10.1134/S2079057014010044

10.1152/ajplung.00212.2010 Am

This relatively high dose changed the view on DMSO toxicity and the FDA classified DMSO in the same class as ethanol, namely class 3 solvent, which is the safest category with low toxic potential at levels normally accepted in pharmaceuticals 8

Oxidative stress is also a contributor to muscle wasting, as ROS are well-known stimulators of apoptotic pathways, showing that oxidative stress is a factor in muscle wasting ( Fig